If you can complete VetMSA with Massive DPS, Can you make a Build with Massive Defenses and no DPS?

Hi everyone, the direction I'm heading with this question is to point out that in the game there are skills and methods to do massive DPS but no build to counter this(Another DPS build does not count). Looking for a Healing or Tanking build that can have sustain defense against builds used in VetMSA. Is the game even built for this?